News

Drawing of macrophages differentiating into M1 and M2 subtypes in pituitary tumors

Interactions with between immune cells and tumor cells have become a large focus in cancer research. A central question in this field revolves around how monocytes and macrophages differentiate into either an M1 subtype, which supresses cancer progression, or an M2 subtype, which enhances it.

MRIs showing before and after surgery for pituitary adenoma
Endoscopic transsphenoidal surgery offers excellent visualization for a giant pituitary adenoma removed at UCSF. Case study by Manish Aghi, MD, PhD.
Image: The G variant of p53 polymorphism rs1042522 drives proliferation in pituitary adenoma cells

Researchers at UCSF have recently discovered a polymorphism in the gene TP53 that influences the growth of non-functional pituitary adenomas (NFPAs). TP53 is known to be dysregulated in many human cancers, including brain cancers. But there have been few studies to date on how it may fit in to the development of pituitary tumors.

The Art of Neuro-Endocrinology Textbook

In a new reference guide, CCPD Medical Director Lewis Blevins Jr., MD, edits a collection of case illustrations that delve into the complexities of medical decision-making. Each case represents a unique and interesting aspect of the evaluation and management of patients with various pituitary disorders.

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