A 55-year-old woman presented with polyuria, nocturia, and thirst-induced polydipsia that developed insidiously over a six-month period. She was seen by her primary physician, who suspected and confirmed a diagnosis of diabetes insipidus. She was treated with DDAVP that provided excellent symptom control. Laboratory studies reflected normal anterior pituitary function. She was otherwise healthy. Physical examination was unrevealing. Magnetic resonance imaging of the sella illustrated a 1.5-cm mass in the region of the hypothalamus.
The California Center for Pituitary Disorders (CCPD) at UCSF was established four years ago as a multidisciplinary center designed to provide comprehensive care to all patients with newly diagnosed and pre-existing pituitary disorders. The program was built on decades of recognized excellence in neurosurgical care and research at UCSF.
Historically, pituitary tumors have been classified as carcinomas if they spread to other tissues in a discontinuous fashion. This implies that a metastasis confirmed and documented by biopsy must be present in a patient with a pituitary tumor before a diagnosis of cancer can be made.