Recognizing that patients with pituitary disorders need coordinated care from a variety of specialists to ensure the best quality of life, the California Center for Pituitary Disorders (CCPD) at UCSF brings expertise from physicians within the disciplines of neurosurgery, neuroendocrinology, neuroradiology, radiation oncology, neuropathology, neurology, neuro-ophthalmology, and psychiatry.
Interactions with between immune cells and tumor cells have become a large focus in cancer research. A central question in this field revolves around how monocytes and macrophages differentiate into either an M1 subtype, which supresses cancer progression, or an M2 subtype, which enhances it.
Researchers at UCSF have recently discovered a polymorphism in the gene TP53 that influences the growth of non-functional pituitary adenomas (NFPAs). TP53 is known to be dysregulated in many human cancers, including brain cancers. But there have been few studies to date on how it may fit in to the development of pituitary tumors.